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[Topical therapy in pregnancy].

A Zesch1

  • 1Institut für Arzneimittel des Bundesgesundheitsamtes Berlin.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|July 1, 1990
PubMed
Summary
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Drug administration during pregnancy requires careful risk-benefit assessment. Some topical medications may pose risks to fetal development, necessitating caution and specific application periods.

Area of Science:

  • Pharmacology
  • Toxicology
  • Obstetrics

Context:

  • Drug administration during pregnancy necessitates careful benefit-risk evaluation.
  • Topical therapies, while generally considered safe, may involve active substances with unknown or relevant embryotoxic potential.
  • Existing data on the safety of many topical agents during pregnancy is limited.

Purpose:

  • To review active substances used in topical therapies during pregnancy.
  • To identify topical medications that should be avoided or used with caution during pregnancy.
  • To highlight the uncertainties and lack of data regarding the safety of certain topical agents.

Summary:

  • This review discusses topical medications applied during pregnancy.
  • Several active substances used in local therapy present potential risks to fetal development.

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  • Recommendations are provided for the use of specific topical agents, with emphasis on periods of application and areas where data is lacking.
  • Impact:

    • Provides guidance for healthcare providers on the safe use of topical medications in pregnant patients.
    • Highlights the need for further research into the safety profiles of topical agents during gestation.
    • Contributes to informed decision-making regarding drug administration in pregnancy to minimize potential harm.