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Updated: May 27, 2026

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Comparative profiling analysis of central metabolites in Euglena gracilis under various cultivation conditions
Fumio Matsuda1, Masahiro Hayashi, Akihiko Kondo
1Organization of Advanced Science and Technology, Kobe University, Kobe, Hyogo, Japan.
Abstract:
Comparative metabolic profiling analysis was performed to investigate light- and aeration-dependent regulation of central metabolism in Euglena gracilis. The metabolic profiles of E. gracilis were significantly altered in response to changes in aeration conditions. While many glycolytic intermediates and amino acids accumulated in aerobically grown E. gracilis, a significant reduction in these metabolites was observed for cells under anaerobic conditions, which resulted in elevated production of wax ester.
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