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Related Experiment Video

Updated: May 27, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Annular elastolytic giant cell granuloma--case report.

Rossana Ruth da Veiga Gonçalves¹, Mario Fernando Ribeiro de Miranda, Fernanda de Oliveira Viana

¹Serviço de Dermatologia, Universidade Federal do Pará, Belém, PA, Brasil.

Anais Brasileiros De Dermatologia

|November 10, 2011

Summary

Annular elastolytic giant cell granuloma, a rare skin condition, showed improvement with hydroxychloroquine treatment. This suggests a potential therapeutic option for this granulomatous disease.

Related Experiment Videos

Last Updated: May 27, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Area of Science:

Dermatology
Pathology

Background:

Annular elastolytic giant cell granuloma is a rare granulomatous skin disease.
It is characterized by elastic fiber phagocytosis by giant cells and presents as annular patches on sun-exposed skin.

Observation:

A 44-year-old woman presented with classic clinical and histological findings of annular elastolytic giant cell granuloma.
Her condition was treated with hydroxychloroquine over a four-week period.

Findings:

The patient's annular elastolytic giant cell granuloma showed significant improvement after four weeks of hydroxychloroquine administration.
Histological examination confirmed the characteristic features of the disease.

Implications:

Hydroxychloroquine may be a potential treatment for annular elastolytic giant cell granuloma.
Further research is warranted to explore the efficacy and safety of hydroxychloroquine for this rare dermatosis.