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Updated: May 27, 2026

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Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
Published on: November 2, 2018
Translational research in retinology
Rubens Camargo Siqueira1, Rodrigo Jorge
1Rubens Siqueira Research Center, São José do Rio Preto, São Paulo, Brazil.
Clinical Ophthalmology (Auckland, N.Z.)
|November 10, 2011
Summary
Clinical laboratory data, including phenotypes and genotypes, are vital for personalized medicine and translational research. This information supports advancements in diagnosing and treating eye diseases through innovative therapies.
Area of Science:
- Clinical laboratory science
- Ophthalmology
- Genomics
- Biomarker research
Background:
- Clinical laboratories generate extensive data on human phenotypes, genotypes, biomarkers, disease progression, and treatment responses.
- This data, both structured and unstructured, is crucial for patient care, personalized medicine, and translational research.
- Laboratory data integration into electronic medical records aids in visualizing longitudinal patient information through summary reports and trending.
Purpose of the Study:
- To highlight the critical role of clinical laboratory data in advancing personalized healthcare.
- To emphasize the potential of laboratory data in translational research, particularly in ophthalmology.
- To underscore the significance of recent ophthalmological advances in diagnosis and treatment.
Main Methods:
- Analysis of the role of laboratory databases in personalized medicine.
- Review of data integration in electronic medical records for patient care.
- Examination of recent advancements in ophthalmology, including gene therapy, stem cell therapy, and retinal prostheses.
Main Results:
- Laboratory data serves as a foundational resource for personalized medicine and translational research.
- Electronic medical records leverage laboratory data for patient monitoring and trend visualization.
- Emerging ophthalmological therapies demonstrate the application of translational research.
Conclusions:
- Clinical laboratories are essential partners in personalized healthcare, providing critical data for patient management and research.
- Translational research, fueled by laboratory data, is driving innovation in the diagnosis and treatment of eye diseases.
- Advances in gene therapy, cell therapy, and retinal prostheses represent a new era in ophthalmology.
