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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

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Spinal dysraphism.

N K Venkataramana¹

¹Department of Neurosurgery, Advanced Neuroscience Institute, BGS Global Hospital, Bangalore, India.

Journal of Pediatric Neurosciences

|November 10, 2011

Summary

Spina bifida, a neural tube defect, presents as aperta or occulta. Early detection and correction of spina bifida are crucial for reducing neurological disability, especially in the Indian scenario.

Area of Science:

Pediatric Neurology
Developmental Biology
Public Health

Background:

Spina bifida is a prevalent congenital anomaly involving neural tube defects.
It is categorized into spina bifida aperta and spina bifida occulta.
Understanding its pathophysiology has evolved significantly, impacting management strategies.

Purpose of the Study:

To review the clinical features of spina bifida.
To discuss the current understanding of spina bifida.
To emphasize the Indian scenario of spina bifida.

Main Methods:

Review of selected articles and current English language texts.
Analysis of authors' experience.
Comprehensive literature review.

Keywords:

Aperta Indian scenario occulta spina bifida tethered cord syndrome

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Main Results:

Prenatal screening has decreased the incidence of spina bifida aperta.
Magnetic resonance imaging has increased the detection of spina bifida occulta.
Evolving understanding of pathophysiology has improved management.

Conclusions:

Early detection and complete surgical correction of spina bifida can substantially minimize neurological deficits.
This review provides an overview of spina bifida, with a focus on the Indian context.