Related Experiment Video
Updated: May 27, 2026
07:55
Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
Published on: August 4, 2011
Retrobulbar primitive neuroectodermal tumor in a squirrel monkey (Saimiri sciureus)
Wijit Banlunara1, Masaya Tsuboi, Kazuyuki Uchida
1Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. wijit.k@chula.ac.th
Journal of Medical Primatology
|November 11, 2011
Summary
A primitive neuroectodermal tumor was diagnosed in a squirrel monkey
Area of Science:
- Veterinary Pathology
- Primate Oncology
- Ophthalmic Pathology
Background:
- A captive-bred squirrel monkey presented with exophthalmos.
- Surgical enucleation revealed a retrobulbar tumor mass.
Observation:
- The tumor adhered to the sclera and infiltrated the choroid.
- Histopathology revealed pleomorphic cells mimicking primitive neuroectodermal cells.
Findings:
- Immunohistochemistry confirmed tumor cells positive for neuronal precursor markers.
- Markers for mature cells and retinoblastoma were negative.
Implications:
- This is the first reported case of a retrobulbar primitive neuroectodermal tumor in non-human primates.
- Contributes to understanding rare tumors in non-human primates.
