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G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome
Published on: March 22, 2018
The SEQanswers wiki: a wiki database of tools for high-throughput sequencing analysis
Jing-Woei Li1, Keith Robison, Marcel Martin
1School of Life Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR. dan.bolser@gmail.com
Nucleic Acids Research
|November 17, 2011
Summary
SEQwiki is a community-driven wiki database addressing challenges in high-throughput sequencing (HTS) data analysis. It offers a comprehensive, up-to-date catalog of HTS tools, technologies, and service providers, aiding researchers in navigating rapid advancements.
Area of Science:
- Bioinformatics
- Genomic Data Management
- Computational Biology
Background:
- High-throughput sequencing (HTS) generates vast data, posing significant management and analysis challenges.
- Rapid technological evolution outpaces traditional scientific publication, leaving a need for current resources.
- Existing resources struggle to keep pace with the dynamic nature of HTS tools and methods.
Purpose of the Study:
- To establish a comprehensive, community-curated database for high-throughput sequencing (HTS) tools and resources.
- To provide an up-to-date and accessible platform for researchers managing and analyzing HTS data.
- To address the growing need for timely information on HTS technologies and service providers.
Main Methods:
- Implementation of a wiki database using MediaWiki with Semantic MediaWiki and Semantic Forms extensions.
- Community-driven content creation, editing, and updating by SEQanswers members.
- Structured data collection for enhanced navigation and reporting features.
Main Results:
- Creation of over 500 tool pages, approximately 400 literature references, and 600 web links within two years.
- Development of a comprehensive catalog of high-throughput sequencing (HTS) tools, technologies, and tutorials.
- Inclusion of task-focused mini-reviews and a directory of over 100 HTS service providers.
Conclusions:
- SEQwiki has become the most extensive online database for high-throughput sequencing (HTS) tools.
- The collaborative, community-driven approach ensures the database remains current and relevant.
- SEQwiki effectively supports researchers in managing and analyzing complex HTS data amidst rapid technological change.
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