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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Changes in Skin Color: Clinical Perspectives

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

Healing II: Complications

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

Pigmentation

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...

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Related Experiment Video

Updated: May 27, 2026

A Two-Step Pyrolysis-Gas Chromatography Method with Mass Spectrometric Detection for Identification of Tattoo Ink Ingredients and Counterfeit Products

A Two-Step Pyrolysis-Gas Chromatography Method with Mass Spectrometric Detection for Identification of Tattoo Ink Ingredients and Counterfeit Products

Published on: May 22, 2019

Rising concern over cosmetic tattoos.

Arisa E Ortiz¹, Tina S Alster

¹Department of Dermatology, University of California at Irvine, Irvine, California, USA.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]

|November 19, 2011

Summary

Cosmetic tattoos are rising in popularity, leading to more adverse reactions. Increased consumer complaints are prompting the Food and Drug Administration (FDA) to investigate tattoo ink safety and regulation.

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Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

Published on: October 18, 2012

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Last Updated: May 27, 2026

A Two-Step Pyrolysis-Gas Chromatography Method with Mass Spectrometric Detection for Identification of Tattoo Ink Ingredients and Counterfeit Products

A Two-Step Pyrolysis-Gas Chromatography Method with Mass Spectrometric Detection for Identification of Tattoo Ink Ingredients and Counterfeit Products

Published on: May 22, 2019

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery

Published on: October 18, 2012

Area of Science:

Dermatology
Cosmetic Science
Regulatory Affairs

Background:

Cosmetic tattoos have gained significant popularity.
This rise has correlated with an increase in reported adverse reactions.
The Food and Drug Administration (FDA) has historically had limited oversight of tattoo inks.

Purpose of the Study:

To increase awareness regarding the potential dangers associated with cosmetic tattoos.
To review the regulatory landscape of tattoo inks.
To highlight the importance of reporting adverse events.

Main Methods:

A comprehensive review of Food and Drug Administration (FDA) policies concerning tattoo inks.
Analysis of common tattoo ink components.
Examination of reported adverse reactions and available treatment modalities for cosmetic tattoo removal.

Main Results:

Growing consumer complaints have initiated an FDA investigation into tattoo ink safety.
Adverse reactions to cosmetic tattoos are a significant concern.
Further reporting of complications is crucial for regulatory action.

Conclusions:

Increased reporting of adverse events is essential for the FDA to establish robust regulations for cosmetic tattoo inks.
Consumer awareness and vigilance are key to ensuring the safety of cosmetic procedures.
The safety of tattoo inks requires ongoing scrutiny and regulatory attention.