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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
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[Frequency of vancomycin-resistant enterococci isolated from blood cultures from 2008 to 2010]

Mira Mihajlović Ukropina1, Zora Jelesić, Vera Gusman

  • 1Institut za javno zdravlje Vojvodine, Novi Sad, Centar za mikrobiologiju. mikrobiologija@izjzv.org.rs

Medicinski Pregled
|November 22, 2011
PubMed
Abstract

Insights

Multidrug-resistant Enterococcus strains, particularly vancomycin-resistant Enterococcus faecium, are a significant concern in hospitals. High resistance rates to common antibiotics necessitate ongoing surveillance to control the spread of these dangerous pathogens.

Area of Science:

  • Clinical microbiology
  • Infectious diseases
  • Antimicrobial resistance

Context:

  • Enterococci are leading causes of hospital-acquired infections worldwide.
  • Enterococcus faecalis and Enterococcus faecium are the most frequently isolated species.
  • Nosocomial pathogens pose a significant threat to patient safety.

Purpose:

  • To determine the prevalence of vancomycin resistance in Enterococcus spp. from blood cultures.
  • To assess resistance patterns to various antimicrobial agents in these isolates.
  • To identify the specific species and resistance phenotypes involved.

Summary:

  • Vancomycin resistance was found in 15.9% of Enterococcus spp. isolates.
  • All vancomycin-resistant strains were identified as Enterococcus faecium with the VanA phenotype.
  • High resistance rates were observed for multiple antibiotics, with notable exceptions for linezolid and quinupristin/dalfopristin.

Impact:

  • The high frequency of multidrug-resistant enterococci underscores the need for vigilant monitoring.
  • Effective strategies are required to prevent and control the dissemination of resistant strains.
  • This study highlights the critical challenge posed by antimicrobial resistance in healthcare settings.

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