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[The relationship between CD44 and immune escape in gastric carcinoma]
Li Sha1, Ren Hui, Ou Jian-feng
1Department of Radiotherapy, Lanzhou General Hospital, Lanzhou Command, Lanzhou 730050, China.
Aim:
To study the relationship between CD44 and gastric carcinoma cells.
Methods:
The rate and mean fluorecence intension of CD44 cells were detected by flow cytometry.
Results:
The rate of CD44' cells was 93.46 ± 3.13% in gastric carcinoma which is higher than 21.27 ± 9. 59% in normal gastric mucosa ( P < 0. 05); The mean fluorecence intension of CD44 in gastric carcinoma was 175. 58 + 49. 21 which was no difference to 141. 02 ± 113.44 in normal gastric mucosa ( P > 0. 05).
Conclusions:
In gastric carcinoma, The increasing of CD44 protein indicated that it may play an important role in the occurrence, development and metabasis of gastric cancer.
