Related Experiment Video
Updated: May 27, 2026
07:35
Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Multicystic dysplastic kidney disease in a dog
Jaehoon Kim1, Hojung Choi, Youngwon Lee
1College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea.
The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
|December 2, 2011
Summary
Multicystic dysplastic kidney disease (MDK) caused anorexia and vomiting in a young dog. This congenital kidney condition was diagnosed post-mortem via necropsy and histopathology.
Area of Science:
- Veterinary Pathology
- Canine Nephrology
- Congenital Malformations
Background:
- Multicystic dysplastic kidney disease (MDK) is a congenital renal disorder characterized by the presence of multiple cysts.
- It can affect various animal species, including dogs, often leading to progressive kidney dysfunction.
Observation:
- A 1-year-old female mongrel dog presented with a 4-day history of anorexia and vomiting.
- Abdominal ultrasonography revealed small kidneys with multiple anechoic cysts, suggestive of MDK.
Findings:
- Post-mortem examination (necropsy) and histopathological analysis confirmed the diagnosis of multicystic dysplastic kidney disease.
- The observed renal morphology was consistent with this developmental anomaly.
Implications:
- This case highlights the clinical presentation and pathological findings of MDK in a young dog.
- Early recognition and understanding of MDK are crucial for veterinary diagnosis and management of renal diseases in canines.
Related Concept Videos
01:25Chronic Kidney Disease I: Introduction
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
01:28Chronic Kidney Disease III: Interprofessional Care
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
01:24Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
01:10Nephrons
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...