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Related Concept Videos

Immunoprecipitation01:20

Immunoprecipitation

Immunoprecipitation, or IP, is a widely used technique that employs protein-antibody interactions to isolate proteins or protein complexes in their native state for studying protein-protein interactions, quaternary structures, or supramolecular complexes. Various modifications of the technique, including chromatin IP, cross-linking IP, and fluorescence IP, are commonly used.
Chromatin Immunoprecipitation
Chromatin immunoprecipitation, also known as ChIP, is used to study protein-DNA or...

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Related Experiment Video

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Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
10:22

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity

Published on: September 16, 2011

The Basel Institute for Immunology.

Fritz Melchers1

  • 1Department of Cell Biology, Biozentrum, University of Basel, CH4056 Basel, Switzerland. fritz.melchers@unibas.ch

Annual Review of Immunology
|December 6, 2011
PubMed
Summary

The Basel Institute for Immunology (BII), a unique research institution, fostered academic freedom and international collaboration. It significantly advanced the understanding of immune system structure and function through extensive research and publications.

Area of Science:

  • Immunology
  • Molecular Biology
  • Biochemistry

Background:

  • Established by Roche in 1968 and operational from 1971 to 2000, the Basel Institute for Immunology (BII) was a pioneering institution.
  • It operated with a unique model of complete academic freedom and no commercial motives, fostering a collaborative international research environment.

Observation:

  • The institute hosted nearly 450 scientific members, over 1,000 scientific visitors, and 100 scientific advisors from over 30 countries.
  • It facilitated over 3,500 research projects, resulting in more than 3,200 scientific publications.

Findings:

  • The BII's research predominantly focused on the structure and functions of immune systems across various species.
  • The institute's work led to significant advancements and a profound scientific impact on the field of immunology.

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Last Updated: May 27, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
10:22

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity

Published on: September 16, 2011

Immunoblot Analysis
16:01

Immunoblot Analysis

Published on: June 20, 2008

Intralymphatic Immunotherapy and Vaccination in Mice
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Intralymphatic Immunotherapy and Vaccination in Mice

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Implications:

  • The BII's legacy highlights the success of an independent, non-commercial research model in driving scientific discovery.
  • Its contributions continue to influence contemporary research in immunology and related life sciences.