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Updated: May 27, 2026

Creation of Abdominal Adhesions in Mice
Published on: August 27, 2016
[Postoperative abdominal adhesions and their prevention in gynaecological surgery: II. How can they be prevented?]
J-L Pouly1, E Darai, C Yazbeck
1Unité de FIV, pôle gynécologie-obstétrique et reproduction humaine, CHU Estaing, 1 place Lucie-Aubrac, Clermont-Ferrand, France. pouly.jean@orange.fr
Abstract:
This paper is the second of a two-part publication. The initial paper provided a comprehensive overview of the evidence on adhesions to allow gynaecological surgeons to be best informed on adhesions, their development, impact on patients, health systems and surgical outcomes. There is rising evidence that surgeons can take important steps to reduce the burden of adhesions. In this second paper, we review the various strategies to reduce the impact of adhesions, improve surgical outcomes and provide some practical proposals for action on adhesions. As well as improvements in surgical technique, developments in adhesion-reduction strategies and new agents offer a realistic possibility of reducing adhesion formation and improving outcomes for patients. They should be considered for use particularly in high-risk surgery and in patients with adhesiogenic conditions. Further research into new strategies to prevent adhesions more effectively through an improved surgical environment, new and combination devices and pharmacological agents should be encouraged. Formal recommendations would ensure better prioritisation of adhesion-reduction within the French health system. Patients should also be better informed of the risks of adhesions.
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