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Published on: September 8, 2021
Development of phyllanthin containing microcapsules and their improved biological activity towards skin cells and
Pik-Ling Lam1, Roberto Gambari, Joanne Yip
1Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hong Kong, China.
Abstract:
Chitosan based microcapsule which encapsulated with phyllanthin was developed by simple coacervation. The composition and surface morphology of phyllanthin containing microcapsules were analyzed by Fourier Transform Infrared spectroscopy and Scanning Electron Microscopy, respectively. The release of phyllanthin from the microcapsules was found to be more than 60% after 120 h. In vitro biological assays demonstrated that these phyllanthin containing microcapsules showed a stronger anti-oxidation potential on both human fibroblasts and keratinocytes as well as a better growth inhibitory activity towards Staphylococcus aureus.
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