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Directing group-controlled hydrosilylation: regioselective functionalization of alkyne

Yuuya Kawasaki1, Youhei Ishikawa, Kazunobu Igawa

  • 1Department of Molecular and Material Sciences, Kyushu University, Kasuga, Fukuoka 816-8580, Japan.

Journal of the American Chemical Society
|December 7, 2011
PubMed
Summary

Platinum-catalyzed hydrosilylation using a dimethylvinylsilyl (DMVS) directing group achieves high regioselectivity for unsymmetric alkynes. This method enables the synthesis of specific silylalkene isomers and diverse functionalized compounds.

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