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Updated: May 26, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
[Treatment with disulfiram can be dangerous]
Skule Arnesen Bakke1, Søren Bjørn Laursen
1Anæstesi og Operationsafdelingen, Sygehus Sønderjylland, Sydvang 1, 6400 Sønderborg, Denmark. skulebakke@hotmail.com
Abstract:
A 66 year-old woman developed severe hypotension and bronchospasm as a result of disulfiram-ethanol reaction (DER). She presented with sudden onset of severe life-threatening symptoms. The clinical signs of DER were treated successfully and symptomatically with intravenous fluids, catecholamines, inhalations and benzodiazepines in the intensive care unit. Fomepizole, an alcohol dehydrogenase inhibitor, was advocated as a specific treatment for DER. This case highlights the potential danger of DER.
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