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Updated: May 26, 2026
07:01
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Invasive follicular thyroid carcinoma infiltrating trachea
Aleksandar Filipović1, Ljiljana Vucković, Milan Mijović
1University of Montenegro, Clinical Centre of Montenegro, Department of Endocrine Surgery, Podgorica, Montenegro. a.filipovic@t-com.me
Vojnosanitetski Pregled
|December 15, 2011
Summary
Radical resection of invasive follicular thyroid cancer infiltrating the trachea, followed by radioiodine therapy, offers a successful treatment option. This approach demonstrated no recurrence in a patient over three years post-surgery.
Area of Science:
- Endocrinology
- Surgical Oncology
- Thyroid Cancer Research
Background:
- Follicular thyroid carcinoma, though rare, can present with invasive growth into surrounding tissues, posing significant management challenges.
- Tracheal infiltration by thyroid cancer requires specialized surgical and therapeutic strategies.
Observation:
- A 66-year-old female presented with an 8 cm left thyroid nodule, confirmed as invasive follicular thyroid cancer with tracheal infiltration.
- Surgical intervention included extended total thyroidectomy with a 2 cm circular tracheal resection and end-to-end anastomosis.
- Post-operative management involved radioiodine therapy and TSH suppressive therapy.
Findings:
- The patient achieved complete resection of the invasive follicular thyroid cancer.
- No evidence of recurrent disease was observed over a three-year follow-up period.
- Combined radical surgical resection and adjuvant therapy proved effective in managing tracheal infiltration.
Implications:
- Radical resection of tracheal-infiltrating thyroid cancer, including tracheal segment resection and anastomosis, is a viable and effective treatment.
- Adjuvant radioiodine therapy and long-term TSH suppression are crucial components of the management strategy.
- This case highlights the importance of aggressive surgical management for advanced thyroid malignancies with local invasion.
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