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Published on: January 16, 2019
Feasibility of continuous multiorgan variability analysis in the intensive care unit
Beverly Bradley1, Geoffrey C Green, Izmail Batkin
1Ottawa Hospital Research Institute, Ottawa, Ontario, Canada K1H 8L6.
Journal of Critical Care
|December 17, 2011
Summary
Continuous monitoring of heart rate variability (HRV) and respiratory rate variability (RRV) using ECG and capnography is feasible in critically ill patients. Data quality is adequate for subsequent analysis, suggesting potential for clinical utility.
Area of Science:
- Critical Care Medicine
- Physiological Monitoring
- Biomedical Engineering
Background:
- Critically ill patients require continuous physiological monitoring.
- Heart rate variability (HRV) and respiratory rate variability (RRV) offer insights into autonomic function.
- Current monitoring methods may have limitations in critically ill populations.
Purpose of the Study:
- To assess the feasibility of continuous HRV and RRV monitoring.
- To utilize electrocardiogram (ECG) and end-tidal capnography (etCO2) waveforms for this monitoring.
- To evaluate the quality of derived variability data in intensive care unit (ICU) patients.
Main Methods:
- Continuous ECG and etCO2 waveform recording in 34 critically ill patients for up to 14 days.
- Analysis of overlapping 5-minute windows using diverse variability measures.
- Evaluation of waveform data quality, disconnections, arrhythmias, and beat/breath detection accuracy.
Main Results:
- Waveform data loss was minimal for ECG (2.9%) and etCO2 (3.1%).
- HRV and RRV data loss due to technical issues or arrhythmias was manageable.
- Successful computation of HRV and RRV was achieved for over 81% and 87% of available data, respectively.
Conclusions:
- Continuous ECG and etCO2 waveform recording provides adequate quality for HRV and RRV monitoring in critically ill patients.
- This pilot study demonstrates the feasibility of continuous multiorgan variability analysis.
- Further research is warranted to explore the clinical utility of this monitoring approach.
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