FDG-PET Quantification of Lung Inflammation with Image-Derived Blood Input Function in Mice

Landon W Locke1, Mark B Williams, Karen D Fairchild

  • 1Department of Biomedical Engineering, The University of Virginia, Charlottesville, VA 22908, USA.

Summary

Dynamic positron emission tomography (PET) imaging quantified lung inflammation in mice infected with Klebsiella pneumoniae. This method revealed a significant increase in glucose uptake, indicating heightened inflammatory responses in the lungs.

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