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A case report on bilateral partial breast irradiation using SAVI.

Aime M Gloi¹, Robert Buchanan, Jeff Nuskind

¹Radiation Oncology, St. Vincent Hospital, Green Bay, WI 54307-3508, USA. agloi@stvgb.org

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists

|December 24, 2011

Summary

This study quantifies dosimetric parameters for bilateral accelerated partial breast irradiation (APBI) using a SAVI device. Results show favorable tumor control probability and low normal tissue complication probability, demonstrating effective APBI delivery.

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Area of Science:

Radiation Oncology
Medical Physics

Background:

Accelerated partial breast irradiation (APBI) is an alternative to whole breast irradiation.
The strut-adjusted volume implant (SAVI) is a brachytherapy device used for APBI delivery.

Observation:

A 59-year-old female patient received bilateral APBI using a SAVI device over 5 days (3.4 Gy twice daily).
Immobilization was achieved with a Vac-lok system, and daily imaging used a C-arm.
Dose-volume histograms (DVHs) were generated to analyze dosimetric parameters.

Findings:

Key dosimetric parameters including D95 (>95%) and V150 (<50 mL) were favorable for both breasts.
Dose homogeneity indices (DHIs) were 0.469 (left) and 0.512 (right).
Calculated tumor control probabilities (TCP) were high (99.2%–99.9%), with low normal tissue complication probabilities (NTCP) (2.57%–4.2%).

Implications:

This case study demonstrates the feasibility and effectiveness of delivering bilateral APBI with a SAVI device.
The dosimetric analysis supports the use of SAVI for precise and safe APBI treatments.
Quantified parameters provide valuable data for optimizing APBI treatment planning and patient outcomes.