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Related Concept Videos

PPE Use in Healthcare Settings I: Donning01:22

PPE Use in Healthcare Settings I: Donning

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Donning PPE must be completed before contact with the patient. This process protects from infectious agents. The sequence and action included in each donning are critical, and the steps must be systematic to avoid exposure to pathogens. The institutional policy also needs to be followed while donning PPE. The pre-donning preparations are gathering equipment, inspecting the PPE equipment for tears, holes, or damage, removing jewelry, removing any garments below the elbows, and tying the hair...
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PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

1.6K
The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
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Related Experiment Video

Updated: May 4, 2026

A Novel Capsulorhexis Technique Using Shearing Forces with Cystotome
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First clinical implementation of the Capri applicator.

Aime M Gloi1

  • 1St Vincent Hospital. agloi@stvgb.org.

Journal of Applied Clinical Medical Physics
|January 16, 2014
PubMed
Summary

The Capri applicator, a multichannel vaginal cylinder, shows promise in reducing rectal radiation dose for endometrial cancer patients. Further follow-up is needed to confirm if this sparing improves clinical outcomes.

Area of Science:

  • Radiation Oncology
  • Gynecologic Oncology
  • Medical Physics

Background:

  • High-dose radiation therapy is crucial for treating high-risk endometrial cancer.
  • Accurate dose delivery and organ-at-risk sparing are essential to minimize toxicity.
  • The Capri applicator offers a novel approach to vaginal brachytherapy with its multichannel design.

Purpose of the Study:

  • To evaluate the dosimetric performance of the Capri applicator in endometrial cancer patients.
  • To assess the ability of the Capri applicator to tailor dose distribution and spare organs at risk.
  • To analyze radiobiological parameters and quality factors for high-dose-rate treatments.

Main Methods:

  • A dosimetric analysis was performed on five high-risk endometrial cancer patients treated with the Capri applicator.

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  • High-radiation doses (21 Gy total) were delivered using a daily fraction of 7 Gy.
  • Treatment plans were evaluated using equivalent uniform dose (EUD), normal tissue complication probability (NTCP), tumor control probability (TCP), and dose-volume histogram (DVH) metrics.

    • Main Results:

    • The Capri applicator achieved high tumor control probability (TCP) values ranging from 82.26% to 95.92%.
    • Low normal tissue complication probability (NTCP) for the bladder and rectum was observed, with low equivalent uniform doses (EUDs) to the rectum.
    • Favorable quality factors including conformity index (CI) and dose homogeneity index (DHI) were reported, indicating precise dose delivery.

    Conclusions:

    • The multichannel Capri applicator demonstrates potential for reducing rectal dose in endometrial cancer patients undergoing high-dose radiation.
    • While rectal dose sparing is promising, bladder dose may be higher, necessitating individualized treatment planning.
    • Further clinical follow-up is required to determine if rectal dose reduction translates to improved clinical toxicity outcomes.