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Doubly committed ventricular septal defect: single-centre experience and midterm follow-up
Charlien Gabriels1, Marc Gewillig, Bart Meyns
1Department of Congenital Cardiology, University Hospitals Leuven, Leuven, Belgium.
Cardiology
|December 30, 2011
Summary
Doubly committed ventricular septal defect (dcVSD) patients who did not undergo closure had few events. However, dcVSD closure led to reduced heart function and increased reoperation risk.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Doubly committed ventricular septal defect (dcVSD) is a rare congenital heart defect.
- Limited research exists on the long-term outcomes of dcVSD.
Purpose of the Study:
- To evaluate the midterm outcomes of patients with doubly committed ventricular septal defect (dcVSD).
- To compare outcomes between patients with persistently patent dcVSD and those who underwent closure.
Main Methods:
- Retrospective review of patient records from University Hospitals Leuven.
- Analysis of clinical, electrocardiographic, and echocardiographic data from baseline (age 16) to follow-up.
- Comparison of outcomes in patients with dcVSD based on closure status.
Main Results:
- Thirty-three patients with dcVSD were followed for a median of 7.9 years.
- No deaths occurred. Fifteen patients (45%) had patent defects at baseline, with 2 spontaneous closures.
- Eighteen patients (55%) required closure before age 16; 5 (28%) needed reoperation, and left ventricular ejection fraction decreased post-closure.
Conclusions:
- Persistently patent dcVSD is associated with a nearly event-free follow-up.
- dcVSD closure is linked to lower event-free survival, reduced left ventricular function, and a high risk of reintervention.
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