Related Experiment Video
Updated: May 26, 2026

11:20
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Primary 23-gauge sutureless vitrectomy for rhegmatogenous retinal detachment
Mario R Romano1, Ronald Das, Carl Groenwald
1St Paul's Eye Unit, Royal Liverpool University Hospital, Prescot Street, L7 8XP, United Kingdom. romanomario@email.it
Indian Journal of Ophthalmology
|January 6, 2012
Summary
This study shows that 23-Gauge transconjunctival sutureless vitrectomy is a safe and effective treatment for primary rhegmatogenous retinal detachment (RRD), with high success rates and improved visual acuity. However, potential complications like hypotony may be higher than with conventional 20-Gauge vitrectomy.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Minimally Invasive Procedures
Background:
- Rhegmatogenous retinal detachment (RRD) is a serious condition requiring surgical intervention.
- Traditional vitrectomy techniques can be invasive.
- Sutureless pars plana vitrectomy offers a minimally invasive alternative.
Purpose of the Study:
- To evaluate the safety and efficacy of 23-Gauge transconjunctival sutureless pars plana vitrectomy for primary RRD.
- To assess anatomical success, functional outcomes, and complications.
Main Methods:
- Prospective, non-comparative interventional study of 50 consecutive patients.
- All surgeries performed using a 23-Gauge transconjunctival sutureless system.
- Minimum of eight clinical visits for follow-up.
Main Results:
- 82% anatomical success with single surgery, 98% with additional procedures.
- Significant improvement in mean visual acuity (logMAR 0.48 to 0.26, P < 0.001).
- Two cases of ocular hypotony with choroidal detachment observed.
Conclusions:
- 23-Gauge transconjunctival sutureless vitrectomy achieves acceptable anatomical and functional success for primary RRD.
- The surgical approach differs from conventional vitrectomy.
- Potential for higher rates of post-surgical hypotony and sclerotomy leakage compared to 20-Gauge vitrectomy.
