Related Experiment Video
Updated: May 26, 2026
E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
A randomized colorectal cancer screening intervention trial in the Iowa Research Network (IRENE): study recruitment
Jeanette M Daly1, Yinghui Xu, John W Ely
1Department of Family Medicine, the University of Iowa, Iowa City, IA, USA. jeanette-daly@uiowa.edu
Background:
Only about half of eligible Americans are adherent with colorectal cancer (CRC) screening. Because patients generally access CRC screening via their primary care physicians, interventions to improve screening should be tested in the primary care setting. This article describes the recruitment and baseline characteristics of patients from 16 practice-based research network practices for a study to improve CRC screening.
Methods:
A total of 8327 invitations were mailed to patients of these practices, and 1685 returned consent forms and baseline surveys.
Results:
Of those who consented, 942 were up to date with screening, which indicates that office databases were unable to provide information about those who were already screened. The 743 due for screening were younger (mean age, 61 vs. 63 years), less likely to have an immediate family member with CRC (11% vs. 19%), less likely to have Medicare (29% vs. 40%), more likely to have no insurance (5% vs. 1%), and less likely to report a physician/nurse recommendation for CRC screening (63% vs. 92%) for all comparisons.
Conclusions:
Our experiences for this practice-based research network randomized clinical intervention trial may be useful to others. Practice and patient recruitment processes were onerous with institutional review board issues, poorly prepared patient databases, and discarding of mail by the US Postal Service.
