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Updated: May 26, 2026

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
Published on: November 17, 2011
6β,8β-Dihy-droxy-eremophil-7(11)-en-8α,12-olide
Zhan-Xin Zhang1, Dong-Qing Fei
1School of Pharmacy, Lanzhou University, Lanzhou 730000, People's Republic of China.
Abstract:
The title compound, C(15)H(22)O(4), an eremophilane sesquiternoid, was isolated from the roots of Ligularia virgaurea. Both six-membered rings (A and B) adopt chair conformations and the five-membered ring is almost planar (r.m.s. deviation = 0.016 Å). The two methyl and two hy-droxy groups adopt a syn conformation and the A/B ring junction is cis-fused. An intra-molecular O-H⋯O hydrogen bond generates an S(6) ring. In the crystal, O-H⋯O hydrogen bonds link the mol-ecules into [100] chains.
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