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Updated: May 26, 2026
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[Extensive Dowling-Degos disease following long term PUVA therapy]
R Kort Khaddar1, W Koubaa Mahjoub, I Zaraa
1Service de dermatologie, EPS La Rabta, Jabbari, Tunis, Tunisie. rymkort@yahoo.fr
Background:
Dowling-Degos disease is a rare and benign inherited dermatosis.
Patients And Methods:
A 53-year-old woman presented with generalized histologically confirmed Dowling-Degos disease revealed 8 years after psoralen photochemotherapy (PUVA) for psoriasis. This presentation was special in terms of its considerable spread as well as the absence of comedone-like and punctate scars.
Discussion:
Dowling-Degos disease is a reticulate pigmentary disorder of the flexures associating prominent comedone-like lesions and pitted scars. Diagnosis is based on clinical and histopathological examination, which allows this entity to be differentiated from other reticulate pigmentary disorders. A literature review failed to provide any indication that PUVA therapy either aggravates or reveals Dowling-Degos disease, a finding which we feel merits mention.
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