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Updated: May 26, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
A quasi-lumped model for the peripheral distortion of the arterial pulse
Panagiotes A Voltairas1, Antonios Charalambopoulos, Dimitrios I Fotiadis
1Department of Materials Science, University of Ioannina, GR 45110 Ioannina, Greece. pvolter@cs.uoi.gr
Abstract:
As blood circulates through the arterial tree, the flow and pressure pulse distort. Principal factors to this distortion are reflections form arterial bifurcations and the viscous character of the flow of the blood. Both of them are expounded in the literature and included in our analysis. The nonlinearities of inertial effects are usually taken into account in numerical simulations, based on Navier-Stokes like equations. Nevertheless, there isn't any qualitative, analytical formula, which examines the role of blood's inertia on the distortion of the pulse. We derive such an analytical nonlinear formula. It emanates from a generalized Bernoulli's equation for an an-harmonic, linear, viscoelastic, Maxwell fluid flow in a linear, viscoelastic, Kelvin-Voigt, thin, cylindrical vessel. We report that close to the heart, convection effects related to the change in the magnitude of the velocity of blood dominate the alteration of the shape of the pressure pulse, while at remote sites of the vascular tree, convection of vorticity, related to the change in the direction of the velocity of blood with respect to a mean axial flow, prevails. A quantitative comparison between the an-harmonic theory and related pressure measurements is also performed.
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