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Updated: May 25, 2026
Flow Cytometric Characterization of Murine B Cell Development
Published on: January 22, 2021
Morphofunctional characteristics of the immune system in CBA and C57Bl/6g mice
V A Shkurupiy1, V O Tkachev, O V Potapova
1Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
Abstract:
We studied peculiarities of morphofunctional organization of the immune system in C57Bl/6g and CBA mice differing by their susceptibility to various types of infectious agents. The revealed differences in the structure of lymphoid organs, T lymphocyte subpopulation ratio and their differentiation into Th1/Th2 cells after mitogen stimulation drove us to a conclusion on genetically determined regularities in the development of the immune response in these animal strains.
