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[Breast implants and anaplastic large cell lymphoma: What do we know?]
J Mychaluk1, D Perignon, Q Qassemyar
1Service de gynécologie obstétrique, centre hospitalier de Compiègne, 60200 Compiègne, France.
Annales De Chirurgie Plastique Et Esthetique
|January 17, 2012
Summary
Anaplastic large cell lymphoma (ALCL) in breast implant patients is a concern. While 41 cases were identified, no direct correlation with prostheses was found, suggesting reassurance but continued vigilance for late complications.
Area of Science:
- Oncology
- Pathology
- Plastic Surgery
Context:
- Growing concern regarding a potential association between breast implants and anaplastic large cell lymphoma (ALCL).
- Need for comprehensive analysis of existing literature to understand this emerging issue.
Purpose:
- To identify and analyze all reported cases of ALCL in patients with breast implants.
- To review published literature from 1991 to 2011 for relevant case studies.
Summary:
- A review of 41 ALCL cases in patients with breast implants was conducted.
- The average patient age was 51, with a mean of 108 months between implantation and diagnosis.
- Over 60% of cases involved aesthetic augmentation; however, no definitive correlation between prostheses and lymphoma was established.
Impact:
- Current evidence does not confirm a direct link between breast implants and ALCL, offering reassurance to patients.
- Highlights the importance of awareness for late-onset seroma or tumefaction in patients with breast implants.
- Emphasizes surgical management, including negative ALK and CD30 expression, as crucial for diagnosis and treatment.
