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Updated: May 25, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
10:51

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

Couple dynamics: PPARγ and its ligand partners.

Shanghai Yu1, H Eric Xu

  • 1VARI-SIMM Center, Center for Structure and Function of Drug Targets, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China.

Structure (London, England : 1993)
|January 17, 2012
PubMed
Summary

Dynamic conformations of ligands and the PPARγ receptor influence transcriptional activity. Understanding these interactions offers new strategies for designing PPARγ-based anti-diabetic drugs.

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