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Updated: May 25, 2026
10:28
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice
Published on: February 18, 2016
[Chronic peripheral arterial disease induced by cocaine]
Sonia Pankl1, Débora Pellegrini, Julio E Bruetman
1Servicio de Clínica Médica, Hospital Británico de Buenos Aires. soniapanki@hotmail.com
Medicina
|January 20, 2012
Summary
Cocaine use can lead to rare peripheral artery blockages, even without other risk factors. Early detection and cessation of cocaine use are crucial for managing this serious cardiovascular complication.
Area of Science:
- Vascular Medicine
- Cardiology
- Toxicology
Background:
- Cocaine use is linked to cardiovascular complications, including peripheral arterial thrombosis.
- Limited data exists on peripheral arterial complications in individuals lacking traditional risk factors.
Observation:
- A 22-year-old female presented with symptoms of peripheral artery disease, including intermittent claudication and left lower limb pain.
- She reported a history of intranasal cocaine use (3 grams/week for one year).
- Diagnostic imaging revealed significant stenosis in the superficial left femoral artery.
Findings:
- The patient's symptoms and imaging findings were attributed to cocaine-induced peripheral arteriopathy.
- Other potential causes for peripheral artery disease were ruled out.
- Treatment with antiplatelet agents, cilostazol, exercise, and substance abuse support led to a positive clinical response.
Implications:
- This case highlights the importance of considering cocaine use in young patients presenting with peripheral arteriopathy, especially when traditional risk factors are absent.
- Educating patients about the cardiovascular risks associated with cocaine consumption is essential.
- Early identification and intervention, including cessation of cocaine use, can improve outcomes for affected individuals.
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