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Lobomycosis (keloidal blastomycosis): case reports and overview
J Fuchs1, R Milbradt, S A Pecher
1Zentrum der Dermatologie und Venerologie, Klinikum der Johann Wolfgang Goethe Universitat Frankfurt, West Germany.
Cutis
|September 1, 1990
Summary
Lobomycosis is a rare fungal skin infection affecting the extremities and earlobes, characterized by keloid-like nodules. Surgical excision is the primary treatment, as chemotherapy is often ineffective for this deep skin disease.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Lobomycosis is a neglected deep fungal infection of the skin, endemic to South and Central America.
- It is caused by the fungus Paracoccidioides (Glenosporella) loboi, which is difficult to culture.
- The disease presents with characteristic skin nodules and plaques, primarily affecting earlobes and extremities.
Observation:
- The abstract details five cases of lobomycosis.
- Clinical presentation includes keloid-like skin nodules and plaques.
- Severe cases exhibit disseminated or confluent nodular lesions covering large skin areas.
Findings:
- Paracoccidioides (Glenosporella) loboi is abundant in lesions but challenging to culture.
- Lobomycosis is generally resistant to chemotherapy.
- Surgical excision can be a successful treatment modality.
Implications:
- Accurate diagnosis is crucial, as lobomycosis is often misdiagnosed due to unfamiliarity.
- Understanding the clinical and microbiological features aids in early identification.
- Further research into effective treatments beyond excision may be warranted.