Inflammatory demyelinating pseudotumor

Inflammatory demyelinating pseudotumor (IDP) is a rare inflammatory lesion of unknown etiology, which presents as a space-occupying lesion but responds dramatically to steroid therapy. The objective of this report is to document 2 cases of IDP seen in Kuwait. Two female patients, aged 35 and 27 years presented with the clinical and radiological features of a space-occupying lesion. Radiological investigations showed partial ring-enhancing lesions with insignificant mass effect, which were multiple in patient one, and single in patient 2. Biopsies in each patient showed features of a demyelinating disorder. Both patients remarkably improved clinically on steroid therapy. The report highlights the need for an early and correct diagnosis of IDP for therapeutic purposes.