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Updated: May 25, 2026
Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment
Published on: June 2, 2023
A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening
Eunha Kim1, Sanghee Lee, Seung Bum Park
1Department of Chemistry/Bio-MAX Institute, Seoul National University, Seoul 151-747, Korea.
Abstract:
We developed a novel fluorescent bioprobe (SF44) that can specifically visualize the cellular lipid droplets in in vitro and in vivo systems and illustrated the mechanistic rationale of its fluorogenic property. Its application to image-based high throughput screening led us to the identification of a new small-molecule modulator of lipid droplet formation.
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