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Engineering a water-soluble cyanine-based probe for plasma butyrylcholinesterase detection and liver injury

Kexin Chen1, Zhiyang Yuwen2, Chenxi Lu1

  • 1Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, P. R. China. liuhongwen@hnu.edu.cn.

Analytical Methods : Advancing Methods and Applications
|August 18, 2026
PubMed

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...