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Updated: May 25, 2026
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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Diversity oriented syntheses of conventional heterocycles by smart multi component reactions (MCRs) of the last
1Department Chemie, Technische Universität München, Lichtenbergstr. 4, Garching 85747, Germany. eckert@tum.de
Abstract:
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.
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