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Related Concept Videos

Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
Gas Chromatography: Types of Detectors-I01:21

Gas Chromatography: Types of Detectors-I

There are different types of detectors used in gas chromatography, each with its own specific properties that make it suitable for detecting certain types of analytes. The most commonly used detectors in GC are thermal conductivity detector (TCD), flame ionization detector (FID), and electron capture detector (ECD).
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Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

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Related Experiment Video

Updated: May 25, 2026

Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope
14:21

Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope

Published on: July 24, 2021

In situ gas sensing using a remotely detectable probe with replaceable insert.

Sun Do Lim1, Kyungsik Ma, Ji Ho Jeong

  • 1Nanophotonics Center, Korea Institute of Science and Technology, Seoul, South Korea.

Optics Express
|January 26, 2012
PubMed
Summary
This summary is machine-generated.

We developed a novel spectroscopic gas sensor using a unique optical fiber probe. This probe, featuring a replaceable insert, is ideal for detecting gases in hazardous environments.

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Operation of Laboratory Photobioreactors with Online Growth Measurements and Customizable Light Regimes
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Last Updated: May 25, 2026

Performing In Situ Closed-Cell Gas Reactions in the Transmission Electron Microscope
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Published on: July 24, 2021

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Published on: October 28, 2021

Area of Science:

  • Optoelectronics
  • Spectroscopy
  • Fiber optics

Background:

  • Optical fiber sensors offer remote and in-situ gas detection capabilities.
  • Existing designs may face limitations in harsh or inaccessible environments.

Purpose of the Study:

  • To demonstrate a novel spectroscopic gas sensor utilizing an optical fiber probe with a replaceable insert.
  • To design a probe capable of gas ingress, light reflection, and pressure regulation for enhanced sensing.

Main Methods:

  • The sensor probe employs a hollow-core photonic bandgap fiber (HC-PBGF) and a hollow core fiber (HCF) insert.
  • The HCF features a gold-coated end facet acting as a gate and reflector.
  • The probe design allows for gas pressure regulation at high flow rates.

Main Results:

  • Successful demonstration of a spectroscopic gas sensor integrated with a specialized optical fiber probe.
  • The probe design facilitates controlled gas entry and efficient light reflection for spectroscopic analysis.
  • The system allows for precise gas pressure regulation within the HC-PBGF.

Conclusions:

  • The developed optical fiber probe represents a significant advancement in spectroscopic gas sensing technology.
  • The probe's design offers potential for reliable gas detection in hazardous environments.
  • This technology could enable remote monitoring and analysis of gases in challenging conditions.