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Updated: May 25, 2026

10:04
Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
Published on: March 13, 2018
PET imaging of tumor growth: not as easy as it looks
1Karmanos Cancer Institute, Department of Oncology, Wayne State University, Detroit, Michigan 48201-2013, USA. ShieldsA@Karmanos.org
Abstract:
Positron emission tomography can be used to image tumor proliferation when combined with appropriate labeled tracers, such as the thymidine analog [(18)F]-3'-deoxy-3'-fluorothymidine. Although thymidine kinase 1 is the principal mechanism of cell trapping, other variables, such as the cellular level of native thymidine, may need to be considered.

