Use of bacterial assay system for monitoring genotoxic complex mixtures in the occupational setting

Workplace environmental genotoxicity assessments, which may be carried out either by laboratory analysis or using an in-situ assay system, are potentially useful for health hazard evaluations, for industrial hygiene and biological (genetic) monitoring. Whenever possible, genotoxicity assays should be performed in conjunction with industrial hygiene studies to assess the biological activity of workplace contaminants. Efforts should continue to be made to establish a simple and reliable in-situ assay system for the detection and monitoring of genotoxic complex mixtures in the occupational setting.