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Updated: May 25, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Surgical risk of transfusion in a French Universitary Hospital]
1Service d'anesthésie-réanimation, hospices civils de Lyon, centre hospitalier Lyon-Sud, université Claude-Bernard Lyon-1, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite cedex, France.
Insights
Preoperative immunohaematology testing relevance varies by surgery type and urgency. Hospitals should tailor transfusion protocols based on their specific surgical data and patient risk factors.
Area of Science:
- Medical Science
- Clinical Pathology
- Surgical Transfusion Medicine
Context:
- Standardized preoperative immunohaematology protocols are widely used.
- Assessing the actual transfusion rates in surgical patients is crucial for protocol relevance.
Purpose:
- To evaluate the necessity of current preoperative immunohaematology testing protocols.
- To analyze transfusion rates across different surgical procedures at a hospital.
Summary:
- A study analyzed 13,571 patients undergoing 44 types of surgery in 2009.
- Transfusion rates varied significantly, from <0.5% for minor procedures to 18.1% for colectomy and 37.8% for emergency hip arthroplasty.
- 45% of transfused patients received transfusions on the day of surgery.
Impact:
- Findings suggest that transfusion risk is highly dependent on surgical procedure and urgency.
- Recommendations for optimizing preoperative immunohaematology testing protocols can be established.
- Hospitals should develop individualized transfusion protocols based on local data and risk assessment.
Introduction:
Immunohaematology examinations are usually prescribed preoperatively according to more or less standardized protocols. We wanted to assess the relevance of these protocols on the basis of factual data: an overview of the rate of transfusions carried out as part of surgery within the HCL in 2009.
Study Design:
The list of patients operated in 2009 in the HCL (IPOP by Cristalnet) has been combined with the list of patients transfused in the same time period (CTS server, Inlog). The percentage of patients transfused during the stay, and the percentage of patients transfused on the day of the intervention itself were determined for each type of surgery. The study focused on 13,571 patients affected by 44 surgeries.
Patients And Methods:
Six hundred and thirty-three patients were transfused, 45% of them the day of the intervention. The risk of needing to carry out a transfusion depends on the risk to the patient and surgery. For example, the total hip arthroplasty transfusion risk is 11.9% when it's programmed against 37.8% in emergency surgery. The transfusion risk of knee arthroscopies, osteosynthesis of wrist fracture, carpal canal surgeries and of appendectomies, thyroidectomies, herna repair surgeries are below 0.5%. The transfusion risk of colectomy is 18.1%. Thus, new recommendations for good clinical practices on the relevance of settled surgery-preoperative immunohematologic exams can be established.
Conclusion:
The emergency degree of the transfusion must be taken into account for such recommendation. Each hospital should perform its own cartography to justify its own protocols.
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