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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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How chemoproteomics can enable drug discovery and development

Raymond E Moellering1, Benjamin F Cravatt

  • 1The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Chemistry & Biology
|January 31, 2012
PubMed
Summary

Integrating chemical proteomic platforms early in drug discovery can identify new therapeutic targets. This approach expands the range of pharmacologically evaluated proteins, aiding the development of first-in-class medications for human diseases.

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