Related Experiment Video
Updated: May 1, 2026
07:03
Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model
Published on: March 18, 2019
6.8K
Postcardiac injury syndrome (part II)
Maria Jaworska-Wilczynska1, Elzbieta Abramczuk, Tomasz Hryniewiecki
1Department of Valvular Heart Disease, Institute of Cardiology, Warsaw, Poland. mjawil@gmail.com
Summary
A patient developed recurrent pericarditis, a complication known as postcardiac injury syndrome (PCIS), after coronary artery bypass surgery. This condition persisted despite anti-inflammatory treatment, highlighting challenges in managing post-cardiac injury syndrome.
Area of Science:
- Cardiology
- Cardiac Surgery
- Inflammatory Diseases
Background:
- Coronary artery bypass surgery (CABG) is a common procedure for coronary artery disease.
- Off-pump coronary artery bypass (OPCAB) surgery is a type of CABG performed without a heart-lung machine.
- Post-pericardiotomy syndrome and postcardiac injury syndrome (PCIS) are known complications following cardiac surgery.
Observation:
- A 58-year-old male patient underwent a 2-vessel off-pump coronary artery bypass surgery (OPCAB).
- One month post-surgery, the patient presented with cardiac tamponade secondary to pericarditis.
- The patient was diagnosed with postcardiac injury syndrome (PCIS).
Findings:
- Despite receiving anti-inflammatory treatment, the patient experienced a relapse of PCIS.
- Recurrent pericarditis indicates a persistent inflammatory response post-cardiac injury.
- The case illustrates the potential for refractory symptoms in PCIS.
Implications:
- This case highlights the need for effective management strategies for relapsing PCIS.
- Further research may be warranted to explore novel therapeutic approaches for post-cardiac injury syndrome.
- Understanding PCIS recurrence is crucial for optimizing patient outcomes after cardiac surgery.
Related Concept Videos
01:17Pericarditis III: Medical Management
586
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
586
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
943
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
943
01:30Acute Coronary Syndrome III: Diagnostic Studies
495
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
495
01:28Acute Coronary Syndrome IV: Interprofessional Care
522
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
522
01:30Cardiomyopathy II: Dilated Cardiomyopathy
790
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
790
01:21Cellular Injury II: Classification
59
Cellular injury is any process that disrupts a cell’s ability to maintain homeostasis, leading to structural or functional changes. It is broadly classified based on etiology (cause) and mechanism of damage.Classification by EtiologyCellular injury may result from several causes. Hypoxic injury happens due to reduced oxygen delivery, most commonly from inadequate blood supply, such as arterial obstruction; for example, coronary artery thrombosis can cause myocardial infarction. Chemical...
59