[The application progresses of the two dimensional electrophoresis in biomedical research]

Research about proteomics is of great significance. Two-dimensional electrophoresis (2-DE) is a core technology of proteomics research, which is used for analysis of the protein extracted from cell, tissue and other sam-nology of proteomics research, which is used for analysis of the protein extracted from cell, tissue and other samples. In recent years, 2-DE combined with mass spectrum (MS) technology is widely used to identify differentialples. In recent years, 2-DE combined with mass spectrum (MS) technology is widely used to identify differential protein, to screen tumor markers, to detect drug targets and so on. Proteomics research has become key technology,protein, to screen tumor markers, to detect drug targets and so on. Proteomics research has become key technology, with its high throughput, high resolution and repeatability, and is widely used in various fields, particularly in bio-with its high throughput, high resolution and repeatability, and is widely used in various fields, particularly in biomedical research. We provided here a short review about the application development of 2-DE, especially its contribution on biological medicine.