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Course and prognosis of ulcerative colitis
L S Chawla1, J S Chinna, J B Dilawari
1Department of Medicine, Dayanand Medical College and Hospital, Ludhiana.
Journal of the Indian Medical Association
|June 1, 1990
Summary
This study on ulcerative colitis (UC) found most patients develop the disease before 50. The chronic intermittent type is most common, with emotional stress and pregnancy as potential triggers.
Area of Science:
- Gastroenterology
- Internal Medicine
- Clinical Research
Background:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
- Understanding UC's clinical course and triggers is crucial for patient management.
Purpose of the Study:
- To analyze the clinical characteristics and course of ulcerative colitis in a cohort of 50 patients.
- To identify common disease patterns, precipitating factors, and complications.
Main Methods:
- Retrospective analysis of 50 ulcerative colitis patients.
- Evaluation of disease onset, activity, clinical course, and precipitating factors.
- Assessment of local and systemic complications.
Main Results:
- Most patients (50) were diagnosed before age 50.
- Severe, moderate, and mild disease activity at onset occurred in 44%, 32%, and 24% respectively.
- Chronic intermittent (48%) and single attack with remission (42%) were the most frequent clinical courses.
Conclusions:
- Ulcerative colitis commonly presents before age 50, with a predominantly chronic intermittent course.
- Emotional disturbances and pregnancy were identified as potential triggers.
- Serious complications were notably absent in this patient cohort.