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Updated: May 25, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
Allergic contact dermatitis caused by a cell phone cover
Penelope Jane Williams1, Clodagh King, Vicky Arslanian
1Department of Dermatology, Royal Liverpool and Broadgreen University Hospitals, NHS Trust, United Kingdom. penster50@hotmail.com
A case of allergic contact dermatitis was caused by a phone cover, leading to further reactions from topical creams. This highlights potential future risks of facial dermatitis from plastic phone accessories.
Area of Science:
- Dermatology
- Allergology
- Materials Science
Background:
- Contact dermatitis is a common skin condition.
- The use of mobile phone accessories, such as covers, is widespread.
- Silicone is often perceived as a hypoallergenic material.
Observation:
- A patient presented with contact dermatitis attributed to a phone cover, initially believed to be solely silicone.
- Secondary allergic contact dermatitis developed from topical creams used to treat the initial rash.
- Patch testing confirmed the phone cover material as the allergen.
Findings:
- The phone cover material elicited a positive patch test reaction.
- Further positive reactions were observed to allergens within the plastics and glues series.
- This indicates the phone cover contained undisclosed chemical components beyond silicone.
Implications:
- The prevalence of mobile phone use and associated accessories may increase the incidence of such allergic reactions.
- Clinicians should consider phone covers as a potential cause of facial dermatitis.
- Undisclosed allergens in plastic manufacturing pose a risk for allergic contact dermatitis.
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