Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...

Heart Failure II: Pathophysiology

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Closure of patent foramen ovale for secondary prevention of cryptogenic stroke: current perspectives.

Archives of medical science : AMS·2020

Same author

The impact of mechanical oesophageal deviation on posterior wall pulmonary vein reconnection.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2019

Same author

Esophageal Deviation During Atrial Fibrillation Ablation: Clinical Experience With a Dedicated Esophageal Balloon Retractor.

JACC. Clinical electrophysiology·2018

Same author

Risk prediction tools for Syncope: The quest for the holy grail.

International journal of cardiology·2018

Same author

The Leadless Cardiac Pacemaker: Conductive Communication.

JACC. Clinical electrophysiology·2018

Same author

Complete Heart Block Complicating ST-Segment Elevation Myocardial Infarction: Temporal Trends and Association With In-Hospital Outcomes.

JACC. Clinical electrophysiology·2018

Search research articles

Related Experiment Videos

Carcinoid heart disease.

Chandrasekar Palaniswamy¹, William H Frishman, Wilbert S Aronow

¹Department of Medicine, Division of Cardiology, New York Medical College/Westchester Medical Center, Valhalla, NY 10595, USA. wsaronow@aol.com

Cardiology in Review

|February 9, 2012

Summary

Carcinoid tumors can lead to carcinoid heart disease, primarily affecting right-sided heart valves. Valve replacement surgery offers significant symptom relief and improved outcomes for patients with severe cardiac involvement.

Related Experiment Videos

Area of Science:

Cardiology
Oncology
Endocrinology

Background:

Carcinoid tumors are rare neuroendocrine tumors.
Carcinoid syndrome involves flushing, diarrhea, bronchospasm, and hypotension.
Cardiac involvement is common and worsens prognosis.

Purpose of the Study:

To review the characteristics and management of carcinoid heart disease.
To evaluate treatment outcomes for carcinoid heart disease.

Main Methods:

Review of literature on carcinoid tumors and carcinoid heart disease.
Analysis of treatment strategies including somatostatin analogs, chemotherapy, surgery, and embolization.

Main Results:

Carcinoid heart disease involves endocardial deposits on heart valves, causing stenosis and regurgitation.
Somatostatin analogs are the primary medical therapy.
Surgical valve replacement improves symptoms and outcomes in severe cases.

Conclusions:

Carcinoid heart disease significantly impacts patient outcomes.
Effective management requires a multidisciplinary approach.
Valve replacement surgery is a viable option for selected patients.