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Structural basis for iron piracy by pathogenic Neisseria

Nicholas Noinaj1, Nicole C Easley, Muse Oke

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|February 14, 2012
PubMed
Summary

Neisseria bacteria use TbpA and TbpB proteins to extract iron from human transferrin. These structural studies reveal how bacteria target transferrin and release iron for survival.

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