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Argon versus krypton panretinal photocoagulation side effects on the anterior segment
U Menchini1, A Scialdone, C Pietroni
1Department of Ophthalmology, University of Milan, Scientific Institute H. S. Rafaele, Italy.
Summary
Argon versus krypton panretinal photocoagulation (PRP) showed comparable side effects on the anterior segment. Both laser treatments for proliferative diabetic retinopathy resulted in similar ophthalmoplegia and reduced corneal sensitivity.
Area of Science:
- Ophthalmology
- Medical Technology
Background:
- Proliferative diabetic retinopathy (PDR) is a severe complication of diabetes.
- Panretinal photocoagulation (PRP) is a standard treatment for PDR.
- Different lasers, such as argon and krypton, are used for PRP, with potential differences in side effects.
Purpose of the Study:
- To compare the effects of argon versus krypton panretinal photocoagulation on anterior segment parameters.
- To evaluate corneal sensitivity, accommodation, pupillary diameter, and endothelial cell density after PRP.
Main Methods:
- Prospective study of 88 eyes from 64 diabetic patients with PDR.
- Patients were randomized to receive either argon or krypton laser PRP.
- Anterior segment parameters were measured at baseline and at 2, 90, and 180 days post-treatment.
Main Results:
- Both argon and krypton PRP caused significant internal ophthalmoplegia and reduced corneal sensitivity.
- No significant differences in these anterior segment parameters were observed between the two laser groups at any time point.
- Endothelial cell loss was slightly, but not significantly, greater in the krypton laser group.
Conclusions:
- Argon and krypton lasers produce comparable side effects on the anterior segment following panretinal photocoagulation for proliferative diabetic retinopathy.
- The choice between argon and krypton laser for PRP does not appear to significantly impact key anterior segment functions or cell density.