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Updated: May 24, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Risk factors for stroke]
1Klinicki centar Nis, Nis, Klinika za fizikalnu medicinu i rehabilitaciju. timmandic@bankerinter.net
Insights
Stroke is a major cause of death and disability worldwide, particularly in Serbia. Identifying and managing modifiable risk factors like hypertension and smoking is crucial for stroke prevention and improving patient outcomes.
Area of Science:
- Neurology
- Public Health
- Cardiovascular Medicine
Context:
- Stroke is a leading cause of mortality globally and the primary cause of death for women over 55 in Serbia.
- Ischemic stroke shares risk factors with ischemic heart disease, including hypertension, dyslipidemia, smoking, inactivity, obesity, and diabetes.
- Stroke patients frequently present with or develop associated medical conditions, complicating management and prognosis.
Purpose:
- To review the epidemiology and risk factors of stroke.
- To highlight the impact of stroke on mortality, disability, and quality of life.
- To emphasize the importance of stroke prevention strategies.
Summary:
- Stroke is a significant global health burden, with modifiable risk factors playing a key role.
- Risk factors are categorized into unmodifiable (age, gender, family history, race) and modifiable (hypertension, diabetes, smoking, obesity, inactivity).
- Potential risk factors include alcohol consumption and hormonal influences.
Impact:
- Stroke survivors face long-term disability, increased fall risk, and higher risk of recurrent cardiovascular events.
- Effective primary and secondary stroke prevention remains a critical medical and social challenge.
- Further research is needed to explore potential risk factors and optimize prevention measures.
Introduction:
Stroke is the third cause of mortality both in men and in women throughout the world. In Serbia, stroke is the first cause of mortality in women older than 55 years of age and the second cause of death in men of the same age. Both ischemic heart diseases and ischemic stroke correlate with the same predisposing, potentially modifiable risk factors (hypertension, abnormal blood lipids and lipoproteins, cigarette smoking, physical inactivity, obesity, diabetes mellitus). Stroke does not usually occur on its own. Patients with stroke have a high prevalence of associated medical problems. These conditions may predict the stroke ("preexisting conditions"), occur for the first time after stroke ("post-stroke complications"), or present as manifestations of preexisting medical conditions after stroke.
Risk Factors:
Risk factors for stroke are divided into the three groups: risk factors which cannot be influenced on such as: age, gender, positive family history of stroke, race: those which are modifiable such as: hypertension, diabetes mellitus, smoking cigarettes, obesity, physical inactivity and the third group consists of potential risk factors for stroke (consumption of alcohol, hormones, changes in fibrinolysis, changes in blood.
Conclusion:
Stroke remains a leading cause of long-term disability and premature death of both men and women. Consequently, stroke survivors are often handicapped and doomed to sedentary lifestyle which restrains performance of activities of daily living, increases the risk for falls, and may contribute to a higher risk for recurrent stroke and cardiovascular disease. Prevention of stroke is still a great medical and social problem. Further studies are required to investigate potential risk factors for the occurrence of stroke as well as the measures of primary and secondary prevention.
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Ischemic Stroke l: Introduction
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Hemorrhagic Stroke ll: Pathophysiology
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