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Updated: May 24, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
Published on: January 7, 2018
A cross-sectional study on food patterns and adiposity among individuals with abnormal glucose homeostasis
Massoud Amini1, Shila Shafaeizadeh, Maryam Zare
1Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Background:
Dietary habits play an important role in the prevention of chronic disease; however, few studies have assessed the major dietary patterns in Middle Eastern countries. This study identifies major dietary patterns among Iranian people with abnormal glucose homeostasis.
Methods:
This cross-sectional study was conducted at the Diabetes Research Center, Isfahan, Iran among 425 subjects with abnormal glucose homeostasis. Patients were of ages 35 - 55 years and had family histories of diabetes. We assessed dietary intake by the use of a food frequency questionnaire (FFQ) that contained 39 food items. General obesity was defined as a BMI ≥ 30 kg/m2 and central obesity was defined as waist circumference (WC) ≥ 88 in women and WC ≥ 102 in men.
Results:
Five major dietary patterns were revealed by factor analysis: 'western', 'healthy', 'vegetarian', 'high-fat dairy', and 'chicken and plants'. Those in the top tertile of the 'western pattern' had greater odds for general (OR = 1.73; 95% CI = 1.07 - 2.78) and central obesity (OR = 2, 95% CI = 1.24 - 3.22), however these associations were not significant after adjustment for confounding variables. The 'high-fat dairy pattern' was associated with greater odds of general obesity only after adjusting for confounding variables (OR = 1.73; 95%CI = 1.01 - 2.96).
Conclusion:
The dietary pattern characterized by high intake of hydrogenated fat and sugar was shown to be positively associated with a risk of general and central obesity, however further prospective studies are required to confirm our findings.
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